Commercial production is scheduled for September, the company said.
Both Artemis Gold and Osisko confirmed on Friday that the province's evacuation order has been lifted for the region.
Ottawa cracked down on mining deals involving foreign state-owned entities in 2022 in a move widely seen as targeting China’s influence in the global critical minerals supply chain.
The company's El Domo-Curipamba project represents Ecuador's next big mine after Mirador and Lundin's Fruta del Norte.